| 세션명 | Korea-Australia Joint Symposium: Functional Macromolecules for Advanced Applications (English) |
|---|---|
| 발표장 | 제8회장 |
| 논문코드 | 1L8-6 |
| 발표일 | 2021-10-21 |
| 발표시간 | 16:25-16:50 |
| 논문제목 | Multifunctional heteroscaled hydrogel integrated with dispersible hybrid nanofibers |
| 발표자 | 차채녕 |
| 발표자 소속 | 울산과학기술원 |
| 저자 | 차채녕† |
| 소속 | 울산과학기술원 |
| 논문초록 | Hydrogels are widely used as scaffolds for cell and tissue culture applications. However, it is challenging to culture cells in 3D hydrogels at higher mechanical stiffness, as diminished permeability leads to limited diffusion of nutrients and available space for sufficient cellular activities. Herein, a novel strategy of incorporating short, aqueous-dispersible nanofibers into hydrogel is presented. Infusing nanofibers into hydrogel without changing the crosslinking density allowed the control of hydrogel mechanics, while limiting the change in permeability. Furthermore, nanofibers with a conductive polymer helped impart electrical conductivity to the hydrogel, allowing more efficient propagation of externally-applied electrical signals through the hydrogels. The resulting multifunctional nanofiber-infused hydrogels, with controllable mechanical and electrical properties, were utilized as a 3D cell culture platform to study the effects of various microenvironmental conditions. |
THE POLYMER SOCIETY OF KOREA